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Evidence-based point-of-care diagnostics: current status and emerging technologies

Chan, Cangel Pui Yee, Mak, Wing Cheung, Cheung, Kwan Yee, Sin, King Keung, Yu, Cheuk Man, Rainer, Timothy and Renneberg, Reinhard 2013. Evidence-based point-of-care diagnostics: current status and emerging technologies. Annual Review of Analytical Chemistry 6 (1) , pp. 191-211. 10.1146/annurev-anchem-062012-092641

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Point-of-care (POC) diagnostics brings tests nearer to the site of patient care. The turnaround time is short, and minimal manual interference enables quick clinical management decisions. Growth in POC diagnostics is being continuously fueled by the global burden of cardiovascular and infectious diseases. Early diagnosis and rapid initiation of treatment are crucial in the management of such patients. This review provides the rationale for the use of POC tests in acute coronary syndrome, heart failure, human immunodeficiency virus, and tuberculosis. We also consider emerging technologies that are based on advanced nanomaterials and microfluidics, improved assay sensitivity, miniaturization in device design, reduced costs, and high-throughput multiplex detection, all of which may shape the future development of POC diagnostics.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: Annual Reviews
ISSN: 1936-1327
Last Modified: 04 Jun 2017 09:15

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