Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Putative anticataract properties of honey studied by the action of flavonoids on a lens culture model

Vit, P. and Jacob, Timothy John Claud 2008. Putative anticataract properties of honey studied by the action of flavonoids on a lens culture model. Journal of Health Science 54 (2) , pp. 196-202. 10.1248/jhs.54.196

Full text not available from this repository.

Abstract

Stingless bee (Meliponini) honey is a bioresource used to treat cataracts in traditional medicine. The anticataract activity of twenty flavonoids was explored in an osmotic cataract model, to find a probable link between the putative anti-cataract properties of stingless bee honey eyedrops and their flavonoids. Osmotic cataracts were induced in ovine lenses to produce a model to test anti-cataract drugs in cultured lenses by digital image analysis. Digital images were taken every 4 hr to monitor progressive opacification by measurements of grey level. In 24 hr. the opacification was stable. Osmotic cataracts were induced by incubating ovine lenses in 45% hypotonic HBS for 24 hr to test the anticataract action of twenty synthetic flavonoids at a concentration of 10-5 M. Luteolin tetramethyl ether, luteolin 4'-glucoside, luteolin 3'-7-diglucoside and orientin, significantly inhibited cataracts induced in ovine lenses incubated in 45% hypotonic HBS for 24 hr. Different degrees of opacification were produced by hypotonic stress in ovine lenses. The significant inhibition of cataracts caused by four derivatives of luteolin in vitro may be considered as a preliminary evidence for the putative anticataract properties of stingless bee honeys.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: The Pharmaceutical Society of Japan
ISSN: 1344-9702
Last Modified: 04 Jun 2017 02:06
URI: http://orca-mwe.cf.ac.uk/id/eprint/9193

Citation Data

Cited 5 times in Google Scholar. View in Google Scholar

Cited 9 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item