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Reversible grasp reflexes in normal pressure hydrocephalus

Thomas, Rhys Huw, Bennetto, Luke and Silva, Mark T. 2009. Reversible grasp reflexes in normal pressure hydrocephalus. Clinical Neurology and Neurosurgery 111 (4) , pp. 387-389. 10.1016/j.clineuro.2008.11.012

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We present two cases of normal pressure hydrocephalus in combination with grasp reflexes. In both cases the grasp reflexes disappeared following high volume cerebrospinal fluid removal. In one of the cases the grasp reflexes returned over a period of weeks but again resolved following definitive cerebrospinal fluid shunting surgery, and remained absent until final follow up at 9 months. We hypothesise that resolving grasp reflexes following high volume CSF removal has both diagnostic and prognostic value in normal pressure hydrocephalus, encouraging larger studies on the relevance of primitive reflexes in NPH.

Item Type: Article
Status: Published
Schools: Medicine
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Uncontrolled Keywords: Normal pressure hydrocephalus; Symptoms/signs; Grasp reflexes
Publisher: Elsevier
ISSN: 0303-8467
Last Modified: 04 Jun 2017 08:59

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