Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations

Houlden, H., Rizzu, P., Stevens, M., de Knijff, P., van Duijn, C. M., van Swieten, J. C., Heutink, P., Perez-Tur, J., Thomas, V., Baker, M., Morris, Huw, Rossor, M., Jannsen, J. C., Petersen, R. C., Dodd, P., Dark, F., Boeve, B., Dickson, D., Davies, P., Pickering-Brown, S., Mann, D., Adamson, J., Lynch, T., Payami, H. and Hardy, J. 1999. Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations. Neuroscience Letters 260 (3) , pp. 193-195. 10.1016/S0304-3940(98)00931-8

Full text not available from this repository.

Abstract

We have assessed whether apolipoprotein E (ApoE) genotype influences the age of onset of dementia in a series of families with frontal temporal dementia with defined mutations in the tau gene. In contrast to the situation in Alzheimer's disease (AD), we could find no evidence that the age of onset of disease was influenced by the ApoE genotype.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher:	Elsevier Scientific Publishers Ireland
ISSN:	0304-3940
Last Modified:	26 Nov 2015 16:13
URI:	https://orca.cardiff.ac.uk/id/eprint/81460

Citation Data

Cited 20 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item