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Development of the Huntington disease work function scale

Brossman, Bradley, Williams, Janet K., Downing, Nancy, Mills, James A., Paulsen, Jane S., Price, Kathleen and Rosser, Anne 2012. Development of the Huntington disease work function scale. Journal of Occupational and Environmental Medicine 54 (10) , pp. 1300-1308. 10.1097/JOM.0b013e31825f30ab

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Abstract

OBJECTIVE: A work function measure specific for persons with prodromal Huntington disease (HD) was created to assist with workplace accommodations. METHODS: A self-report HD Work Function (HDWF) measure was developed from focus group and expert validation. RESULTS: Pilot studies with 238 people with prodromal HD, and 185 companions; and 89 people without prodromal HD, and 70 companions indicate that HDWF has acceptable internal consistency (Cronbach α = 0.77), acceptable interrater reliability (r = 0.58), and acceptable convergent validity with selected items from the Endicott Work Productivity Scale (r = -0.56), Social Adjustment Scale-Self Report (r = -0.29), and Everyday Cognition (r = -0.70). The HDWF can distinguish between people with prodromal HD and people with an HD family history who do not have prodromal HD (P < 0.0001). CONCLUSIONS: The HDWF is a brief self-assessment that may be used to monitor work function.

Item Type: Article
Date Type: Publication
Status: Published
Schools: MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Medicine
Neuroscience and Mental Health Research Institute (NMHRI)
Subjects: R Medicine > R Medicine (General)
Additional Information: Kathleen Price and Anne Rosser are collaborators on this article.
Publisher: Lippincott Williams & Wilkins
ISSN: 1076-2752
Last Modified: 04 Jun 2017 08:29
URI: http://orca-mwe.cf.ac.uk/id/eprint/79145

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