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Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain

Brancale, Andrea, McGuigan, Christopher, Andrei, G., Snoeck, R., De Clercq, E. and Balzarini, J. 2000. Bicyclic nucleoside inhibitors of Varicella-Zoster Virus (VZV): the effect of a terminal halogen substitution in the side-chain. Bioorganic & Medicinal Chemistry Letters 10 (11) , pp. 1215-1217. 10.1016/S0960-894X(00)00193-1

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Abstract

Preliminary SAR studies on the side chain of a new class of antiviral nucleosides have shown that terminal substitution in the side-chain, with a halogen atom, lead to potent and highly speci®c anti-VZV agents.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Pharmacy
Systems Immunity Research Institute (SIURI)
Subjects: R Medicine > RS Pharmacy and materia medica
ISSN: 0960894X
Last Modified: 18 Oct 2017 13:44
URI: http://orca-mwe.cf.ac.uk/id/eprint/7490

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