Guideline for the prevention of acute nausea and vomiting due to antineoplastic medication in pediatric cancer patients

Dupuis, L. Lee, Boodhan, Sabrina, Holdsworth, Mark, Robinson, Paula D., Hain, Richard, Portwine, Carol, O'Shaughnessy, Erin and Sung, Lillian 2013. Guideline for the prevention of acute nausea and vomiting due to antineoplastic medication in pediatric cancer patients. Pediatric Blood and Cancer 60 (7) , pp. 1073-1082. 10.1002/pbc.24508

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Abstract

This guideline provides an approach to the prevention of acute antineoplastic-induced nausea and vomiting (AINV) in children. It was developed by an international, inter-professional panel using AGREE and CAN-IMPLEMENT methods. Evidence-based interventions that provide optimal AINV control in children receiving antineoplastic agents of high, moderate, low, and minimal emetogenicity are recommended. Recommendations are also made regarding selection of antiemetic agents for children who are unable to receive corticosteroids for AINV control, the role of aprepitant and optimal doses of antiemetic agents. Gaps in the evidence used to support the recommendations were identified. The contribution of this guideline to AINV control in children requires prospective evaluation. Pediatr Blood Cancer 2013; 60: 1073–1082. © 2013 Wiley Periodicals, Inc.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Uncontrolled Keywords:	antiemetics;antineoplastic-induced nausea and vomiting;antineoplastics;chemotherapy-induced nausea and vomiting;nausea;vomiting
Publisher:	Wiley-Blackwell
ISSN:	1545-5009
Funders:	Pediatric Oncology Group of Ontario, Ministry of Health and Long Term Care, Ontario, Children's Oncology Group
Date of Acceptance:	29 January 2013
Last Modified:	19 Mar 2016 23:56
URI:	https://orca.cardiff.ac.uk/id/eprint/73524

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