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A review on the mechanism of sore throat in tonsillitis

Bathala, S. and Eccles, Ronald ORCID: https://orcid.org/0000-0001-9492-2062 2013. A review on the mechanism of sore throat in tonsillitis. The Journal of Laryngology & Otology 127 (03) , pp. 227-232. 10.1017/S0022215112003003

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Abstract

Background: Sore throat is a common condition associated with acute upper respiratory tract infection, and recurrent episodes of infection may result in chronic tonsillitis. The current UK and USA guidelines for tonsillectomy use the incidence of sore throat episodes as an indication for surgery. However, the mechanism of sore throat is poorly described in the literature. Objectives: This review will provide basic information for the clinician regarding: the causes, pathophysiology and neurophysiology of sore throat; the mechanism of inflammation; and the role of transient receptor potential ion channels as nociceptors involved in sore throat. The review will present new ideas on the mechanism of ice therapy as an analgesic for post-tonsillectomy pain, and the role of vanilloid and cold receptors.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Subjects: Q Science > QR Microbiology > QR355 Virology
Publisher: Cambridge University Press
ISSN: 0022-2151
Last Modified: 28 Oct 2022 08:42
URI: https://orca.cardiff.ac.uk/id/eprint/71791

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