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Generation and modulation of cytosolic Ca2+ signals in pancreatic acinar cells: Techniques and mechanisms

Dolman, N. J., Tepikin, Alexei and Petersen, Ole Holger 2003. Generation and modulation of cytosolic Ca2+ signals in pancreatic acinar cells: Techniques and mechanisms. Biochemical Society Transactions 31 (5) , pp. 947-949.

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Abstract

Calcium is a ubiquitous signalling molecule, known to control a vast array of cellular processes. In order to retain stimulus fidelity, the cell encodes the increases in intracellular calcium in the form of oscillations that are regulated both temporally and spatially. Here, we review recent work, using the pancreatic acinar cell as a model system, on the mechanisms employed to generate and modulate cytosolic Ca(2+) signals, and the technical advances that have made these studies possible.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Systems Immunity Research Institute (SIURI)
Subjects: Q Science > QH Natural history > QH426 Genetics
Publisher: Portland Press
ISSN: 0300-5127
Last Modified: 04 Jun 2017 08:01
URI: http://orca-mwe.cf.ac.uk/id/eprint/71677

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