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Peripheral neuropathy during longterm high-dose amiodarone therapy

Fraser, Alan Gordon, McQueen, I. N., Watt, A. H. and Stephens, M. R. 1985. Peripheral neuropathy during longterm high-dose amiodarone therapy. Journal of Neurology, Neurosurgery & Psychiatry 48 (6) , pp. 576-578. 10.1136/jnnp.48.6.576

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Three patients developed peripheral neuropathy after taking amiodarone for more than 18 months. All had high serum concentrations of amiodarone and its desethyl metabolite; in one patient concentrations in a sural nerve biopsy were 80 times higher than in serum. Peripheral neuropathy is a complication of large doses of amiodarone taken over long periods.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Publisher: BMJ Publishing Group
ISSN: 0022-3050
Last Modified: 04 Jun 2017 07:49

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