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Cloning and unusual expression profile of the aldolase B gene from Atlantic salmon

Llewellyn, Lynda, Sweeney, Glen E., Ramsurn, Vimi P., Rogers, Sarah A. and Wigham, Trevor 1998. Cloning and unusual expression profile of the aldolase B gene from Atlantic salmon. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1443 (3) , pp. 375-380. 10.1016/S0167-4781(98)00229-2

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A full-length clone of the aldolase B gene has been isolated from a cDNA library constructed from liver of Atlantic salmon (Salmo salar). Sequencing showed that the clone encodes a typical aldolase B, possessing a number of amino acid residues which are seen in aldolase B, but not in other aldolase isoforms. RT-PCR analysis showed that the gene is expressed in liver, kidney and intestine as expected. However, in contrast to mammalian and avian aldolase B, expression was also found in a number of other tissues. Levels of aldolase B mRNA in liver and kidney were not significantly altered during smoltification, the transformation of freshwater-dwelling salmon (parr) into saltwater-adapted salmon (smolts).

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Publisher: Elsevier
ISSN: 0167-4781
Last Modified: 02 May 2019 10:59

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