Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Phytoestrogen concentrations in serum from Japanese men and women over forty years of age

Morton, Michael S., Arisaka, Osamu, Miyake, Noriko, Morgan, Liam David and Evans, Bronwen Alice James 2002. Phytoestrogen concentrations in serum from Japanese men and women over forty years of age. Journal of Nutrition 132 (10) , pp. 3168-3171.

Full text not available from this repository.


Asian individuals have much lower incidences of prostate and breast cancer than populations from Western developed countries. They also consume a lower fat, higher fiber diet, with a large intake of phytoestrogens. These phytoestrogens may protect against hormone-dependent cancers and other diseases. Our study used established gas chromatography-mass spectrometry (GC-MS) methodologies to measure the concentrations of four phytoestrogens (daidzein, genistein, equol and enterolactone) in serum samples obtained from Japanese men (n = 102) and women (n = 125) > 40 y old. The results were compared with those obtained with samples from the UK. The Japanese men and women had higher (P < 0.001) concentrations of circulating daidzein, genistein and equol than individuals from the UK. The mean concentration of genistein in Japanese men, for example, was 492.7 nmol/L, compared with 33.2 nmol/L in men from the UK. The two populations, however, had similar serum concentrations of enterolactone. Furthermore, 58% of the Japanese men and 38% of the Japanese women had equol concentrations > 20 nmol/L, compared with none of the UK men and 2.2% of the UK women. These results support previously published GC-MS results from studies with low numbers of samples.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Uncontrolled Keywords: phytoestrogens; soy; Japanese; serum
Publisher: Rockville, MD : American Society for Nutrition
ISSN: 0022-3166
Last Modified: 19 Jul 2018 20:43

Citation Data

Cited 252 times in Google Scholar. View in Google Scholar

Cited 220 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item