Antibodies to xanthine oxidase: elevated levels in patients with acute myocardial infarction

Harrison, R., Benboubetra, Mustapha, Bryson, S., Thomas, R. D. and Elwood, Peter Creighton 1990. Antibodies to xanthine oxidase: elevated levels in patients with acute myocardial infarction. Cardioscience 1 (3) , pp. 183-189.

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Abstract

Circulating antibodies to whole dried cows' milk, previously reported to be elevated in patients with myocardial infarction, have been shown to be directed mainly to the bovine milk fat globule membrane. Human antibodies against the bovine milk fat globule membrane themselves interact primarily with the enzyme, xanthine oxidase. Comparison of anti-(xanthine oxidase) antibody levels in 107 patients, who had suffered a myocardial infarction, with those in 86 control subjects showed significantly higher IgM levels in the patients with myocardial infarction. No corresponding differences were found for IgG or IgA anti-(xanthine oxidase) antibodies. Total levels of IgM class immunoglobulins did not differ between patients and controls. Serial assays following myocardial infarction showed no evidence that raised levels of IgM anti-(xanthine oxidase) antibodies result from the infarction itself.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine Pharmacy
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Publisher:	Canal Press
ISSN:	1015-5007
Last Modified:	10 Jun 2023 01:17
URI:	https://orca.cardiff.ac.uk/id/eprint/64584

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