Cell-based therapies for Parkinson's disease

Foster, George A. and Stringer, Bradley M. J. 2004. Cell-based therapies for Parkinson's disease. Drug Discovery Today: Therapeutic Strategies 1 (1) , pp. 43-49. 10.1016/j.ddstr.2004.08.004

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Abstract

A restorative therapy for a disease such as Parkinson's, where substantial cellular degeneration has already occurred at the time of diagnosis, is likely to require a more complex intervention than simply enhancing dopamine output in the brain. Here we assess the value and feasibility of a variety of strategies aimed at either replacing the lost neuronal circuitry or providing one-off delivery of corrective and/or neuroprotective genes.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Publisher:	Elsevier
ISSN:	1740-6773
Last Modified:	25 Oct 2016 03:43
URI:	https://orca.cardiff.ac.uk/id/eprint/63345

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