Radial glial cells: defined and major intermediates between embryonic stem cells and CNS neurons

Götz, Magdalena and Barde, Yves-Alain ORCID: https://orcid.org/0000-0002-7627-461X 2005. Radial glial cells: defined and major intermediates between embryonic stem cells and CNS neurons. Neuron 46 (3) , pp. 369-372. 10.1016/j.neuron.2005.04.012

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Abstract

Radial glial cells have been identified as a major source of neurons during development. Here, we review the evidence for the distinct “glial” nature of radial glial cells and contrast these cells with their progenitors, the neuroepithelial cells. Recent results also suggest that not only during neurogenesis in vivo, but also during the differentiation of cultured embryonic stem cells toward neurons, progenitors with clear glial antigenic characteristics act as cellular intermediates.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Biosciences
Publisher:	Elsevier
ISSN:	0896-6273
Last Modified:	27 Oct 2022 08:26
URI:	https://orca.cardiff.ac.uk/id/eprint/62293

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