Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Cloning and sequence analysis of the human parathyroid hormone gene region

Reis, A., Hecht, W., Gröger, R., Böhm, I., Cooper, David Neil, Lindenmaier, W., Mayer, H. and Schmidtke, J. 1990. Cloning and sequence analysis of the human parathyroid hormone gene region. Human Genetics 84 (2) , pp. 119-124. 10.1007/BF00208924

Full text not available from this repository.


A region of 50 kb around the human PTH gene was cloned and mapped by restriction analysis. Sequence analysis was performed and 3270bp determined, completing the sequence of the gene. The nucleotide sequence was analysed with regard to homology between human, bovine and rat PTH genes, and various potential cis-acting regulatory elements were identified. The gene region lacks an obvious CpG island. The PTH gene region in patients suffering from (pseudo)-hypoparathyroidism was investigated by Southern blotting. No detectable alteration in the fragment patterns was observed. Results of segregation analysis in families with affected individuals was inconclusive.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
Publisher: Springer
ISSN: 0340-6717
Last Modified: 04 Jun 2017 06:33

Citation Data

Cited 18 times in Google Scholar. View in Google Scholar

Cited 20 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item