The effect of topically applied progesterone on sebum excretion rate

Simpson, N. B., Bowden, Paul Edward, Forster, R. A. and Cunliffe, W. J. 1979. The effect of topically applied progesterone on sebum excretion rate. British Journal of Dermatology 100 (6) , pp. 687-692. 10.1111/j.1365-2133.1979.tb08073.x

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Abstract

There is evidence that anti-androgens may help in the treatment of acne vulgaris. We therefore performed a double-blind trial to assess the effect of topically applied progesterone on sebum excretion rate. Thirty-eight patients took part in the trial which was for 3 months. The preparation had no etfect in males. However, a signiticant reduction in sebum excretion rate was found in females, the etfect being maximal at the end of the second month. There was a significant loss of effect at the end of the third month and this was not related to deterioration of the progesterone preparation.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Subjects:	R Medicine > R Medicine (General) R Medicine > RL Dermatology
Publisher:	Wiley-Blackwell
ISSN:	0007-0963
Last Modified:	12 Jun 2019 02:24
URI:	https://orca.cardiff.ac.uk/id/eprint/57804

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