The synthesis of triphosphine ligands and their macrocycles

Hollamby, Tom 2013. The synthesis of triphosphine ligands and their macrocycles. MPhil Thesis, Cardiff University. Item availability restricted.

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Abstract

A new synthesis is described for the production of a single monodentate aromatic phosphine ligand for coordination to a metal centre. 2-fluorophenyl phosphine was synthesised in good yield and has been coordinated to a variety of metal centres. There seems to be no inhibiting factors preventing the phosphine coordinating to any metal centres in a facial manner. Further investigation will be required to see if the 2-fluorophenyl phosphine can be cyclised with a suitable base before the macrocycle can be liberated from the metal centre. Linear triphosphine ligands have previously been reported to coordinate to metal centres as tridentate chelating ligands. Cyclisation to produce the macrocycle has been achieved through cyclocondensation reactions utilising high dilution, high temperature techniques. Reported here is a new synthetic route to a linear triphosphine by coupling benzyl phosphine with two equivalents of vinyl phosphonate before it’s reduction using lithium aluminium hydride. An attempted cyclisation of the triphosphine utilising calcium iodide as the metal centre in a template synthesis is described.

Item Type:	Thesis (MPhil)
Status:	Unpublished
Schools:	Chemistry
Subjects:	Q Science > QD Chemistry
Date of First Compliant Deposit:	30 March 2016
Last Modified:	19 Mar 2016 23:28
URI:	https://orca.cardiff.ac.uk/id/eprint/53185

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