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Dinuclear double-stranded metallosupramolecular ruthenium complexes: Potential anticancer drugs

Hotze, Anna C. G., Kariuki, Benson and Hannon, Michael J. 2006. Dinuclear double-stranded metallosupramolecular ruthenium complexes: Potential anticancer drugs. Angewandte Chemie International Edition 45 (29) , pp. 4839-4842. 10.1002/anie.200601351

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Abstract

Just add a twist: Metallosupramolecular architecture design is used to create anti-cancer agents with high activities in human breast cancer cell lines. Three isomers, which comprise a nonhelical metallocyclophane, an unsaturated double helicate, and a new type of double helicate, bridge the fields of metallosupramolecular architecture and anticancer drug design (picture: double-helical trans/cis isomer; red Ru, green Cl).

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
R Medicine > RM Therapeutics. Pharmacology
Publisher: Wiley-Blackwell
Last Modified: 04 Jun 2017 04:59
URI: http://orca-mwe.cf.ac.uk/id/eprint/47235

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