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On the regiochemistry of Mitsunobu alkylations of hydrazine derivatives

Dunford, Damian G., Chaudhry, Faryal, Kariuki, Benson, Knight, David William and Wheeler, Robert C. 2012. On the regiochemistry of Mitsunobu alkylations of hydrazine derivatives. Tetrahedron Letters 53 (51) , pp. 7006-7009. 10.1016/j.tetlet.2012.10.084

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Abstract

That differentially protected hydrazines of the type TsNHNHCOR3 undergo regiospecific Mitsunobu reactions with a variety of alcohols, R1R2CHOH in a generalised manner, to give good to excellent yields of the mono-adducts Ts(R1R2CH)NNHCOR3, has been proven by X-ray crystallographic analysis.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Cardiff Catalysis Institute (CCI)
Subjects: Q Science > QD Chemistry
Publisher: Elsevier
ISSN: 0040-4039
Last Modified: 04 Jun 2017 04:59
URI: http://orca-mwe.cf.ac.uk/id/eprint/47162

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