Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

An alternative strategy to the Pictet-Spengler method for tetrahydroisoquinoline synthesis: a feasibility study

Henderson, Laura, Knight, David William and Williams, Andrew C. 2012. An alternative strategy to the Pictet-Spengler method for tetrahydroisoquinoline synthesis: a feasibility study. Tetrahedron Letters 53 (35) , pp. 4657-4660. 10.1016/j.tetlet.2012.06.091

Full text not available from this repository.

Abstract

Acid-catalysed cyclisations of the 2-aminoethyl styrene derivatives 9 give good to excellent yields of the corresponding tetrahydroisoquinolines 7 by an intramolecular hydroamination reaction, which represents an alternative and potentially more flexible strategy to the classical Pictet–Spengler method for the syntheses of such heterocycles.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Cardiff Catalysis Institute (CCI)
Subjects: Q Science > QD Chemistry
Uncontrolled Keywords: Pictet–Spengler; Alternative; Hydroamination; Acid-catalysed; Cyclisation
Publisher: Elsevier
ISSN: 0040-4039
Last Modified: 06 May 2023 01:29
URI: https://orca.cardiff.ac.uk/id/eprint/45501

Citation Data

Cited 8 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item