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The Dermatology Life Quality Index (DLQI) and EuroQol-5D (EQ-5D): is there a correlation between these two measures? [Abstract]

Basra, Mohamed K. A., Cruz, P., Finlay, Andrew Yule, Piguet, Vincent and Salek, Mir-saeed 2012. The Dermatology Life Quality Index (DLQI) and EuroQol-5D (EQ-5D): is there a correlation between these two measures? [Abstract]. Journal of Investigative Dermatology 132 (S2) , S72. 10.1038/jid.2012.300

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The use of the DLQI and the EQ-5D is increasing in dermatology clinical research. A formula has been derived from psoriasis patients’ data to describe the relationship between the two measures: EQ-5D utility score=0.956-[0.0248 × (DLQI score)]. The aim of this study was to review the current published evidence concerning the relationship between DLQI and EQ-5D scores derived from studies on different dermatoses and to provide guidance over the conversion of scores. An online and manual literature search was conducted to identify studies published in English that used both the DLQI and the EQ-5D together. The search terms included: DLQI, EQ-5D, skin disease, dermatology, quality of life, preference-based measures, utility measures. Twenty articles and three abstracts were identified that described the use of both the EQ-5D and DLQI in the same study. Six articles were cross sectional epidemiological studies. Two articles and one abstract described the cost-utility and cost-effectiveness of interventions. Three articles and two abstracts examined the relationship between PROs and clinical outcomes. Eight articles assessed the QoL improvement following treatment for psoriasis and one article following treatment for venous eczema. Correlation coefficients between the DLQI and EQ-5D were described only in six studies. Data were identified from the 14 studies that gave both DLQI and EQ-5D values and these data were used to calculate the overall mean correlation between the DLQI and EQ-5D i.e. r=0.68. This relationship is represented by the equation: EQ-5D utility score=0.9297-[0.0219 × (DLQI score)]. These results show a moderate level of correlation between the DLQI and EQ-5D based on published data. Moreover, there appears to be close similarity between the conversion formula derived from original research and the secondary analysis of published values.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Systems Immunity Research Institute (SIURI)
Subjects: R Medicine > RM Therapeutics. Pharmacology
Publisher: Nature Publishing Group
ISSN: 0022-202X
Last Modified: 04 Jun 2017 04:33

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