Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Quantified measurement of activity provides insight into motor function and recovery in neurological disease

Busse, Monica, Pearson, Owen R., Van Deursen, Robert William Martin and Wiles, Charles Mark 2004. Quantified measurement of activity provides insight into motor function and recovery in neurological disease. Journal of Neurology Neurosurgery & Psychiatry 75 (6) , pp. 884-8. 10.1136/jnnp.2003.020180

Full text not available from this repository.

Abstract

Background: A direct quantitative measurement of locomotor activity in an individual’s own environment over an extended period may help in evaluating the impact of impairments in neurological disorders. Objective: To investigate the reliability and validity of activity monitoring in neurological patients and healthy subjects. Methods: Initial reliability studies were completed on 10 healthy subjects and 10 mobility restricted neurological patients. Validity was investigated using 7 days of ambulatory monitoring with the Step Watch™ step activity monitor, laboratory based measures of gait and the Rivermead Mobility Index (RMI) in 10 patients with multiple sclerosis, 10 with Parkinson’s disease, and 10 with a primary muscle disorder. Additionally, 30 healthy subjects participated in the study. Two clinical illustrations of ambulatory monitoring are provided. Results: The mean (range) right step count of 7 days of monitoring in both healthy and neurological patients proved a reliable measure of activity (intra-class correlations 0.89 and 0.86 respectively). The 7 day mean (range) right step count was 5951 (2886?9955) in healthy subjects, 3818 (1611?5391) in patients with Parkinson’s disease, 3003 (716?5302) in those with muscular disorders, and 2985 (689–5340) in those with multiple sclerosis. A moderate correlation was noted between 7 day mean step count and gait speed (r?=?0.45, p?=?0.01) in the grouped neurological patients but not the RMI (rs?=?0.3, p?=?0.11). Conclusion: Ambulatory monitoring provides a reliable and valid measure of activity levels. Neurological patients, living independently, demonstrate lower activity levels than healthy matched controls. Ambulatory monitoring as an outcome measure has potential for improving the evaluation of ambulation and providing insight into participation.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Healthcare Sciences
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
ISSN: 0022-3050
Last Modified: 04 Jun 2017 01:32
URI: http://orca-mwe.cf.ac.uk/id/eprint/374

Citation Data

Cited 96 times in Google Scholar. View in Google Scholar

Cited 76 times in Scopus. View in Scopus. Powered By Scopus® Data

Cited 67 times in Web of Science. View in Web of Science.

Actions (repository staff only)

Edit Item Edit Item