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Guidelines for prescribing azathioprine in dermatology

Anstey, Alexander Vincent, Wakelin, S. and Reynolds, N. J. 2004. Guidelines for prescribing azathioprine in dermatology. British Journal of Dermatology 151 (6) , pp. 1123-1132. 10.1111/j.1365-2133.2004.06323.x

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Azathioprine has been available as an immunosuppressive agent for over 40 years, and current routine usage in dermatology is not restricted to licensed indications. Advances in understanding the metabolic fate of azathioprine have led to significant changes in prescribing practice and toxicity monitoring by U.K. dermatologists. The current state of knowledge concerning the use of azathioprine in dermatology is summarized, with identification of strength of evidence. Clinical indications and contraindications for azathioprine usage in dermatology are identified. Evidence-based recommendations are made for routine safety monitoring of patients treated with azathioprine, including pretreatment assessment of red blood cell thiopurine methyltransferase activity.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
R Medicine > RL Dermatology
Publisher: Wiley-Blackwell
ISSN: 0007-0963
Last Modified: 19 Mar 2016 23:03

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