Microfluidic device for compositional analysis of solvent systems at microwave frequencies

Rowe, David James, Porch, Adrian, Barrow, David Anthony and Allender, Christopher John 2012. Microfluidic device for compositional analysis of solvent systems at microwave frequencies. Sensors and Actuators B: Chemical 169 , pp. 213-221. 10.1016/j.snb.2012.04.069

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Abstract

A device for analysing the chemical composition of single- and multi-phase solvent flows using microfluidic dielectric spectroscopy is demonstrated in this work. An open-circuited, half-wavelength, coaxial resonator operating at microwave frequencies (i.e. harmonics of 600 MHz) was embedded in a compression-sealed polytetrafluoroethylene microfluidic chip for in situ characterization of solvent–solvent and solute–solvent mixtures of varying concentration, and an aqueous–organic segmented flow. Results are shown for a solvent mixture of acetonitrile in toluene as a test system, exhibiting a sensitivity limit of 400 nM. In addition to being highly sensitive, the measurement system is fast, robust and non-invasive, and can be readily miniaturized.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Engineering Pharmacy
Subjects:	T Technology > TA Engineering (General). Civil engineering (General)
Uncontrolled Keywords:	Dielectric measurements; Microwave sensors; Microfluidics
Publisher:	Elsevier
ISSN:	0925-4005
Last Modified:	09 Jul 2020 14:59
URI:	http://orca-mwe.cf.ac.uk/id/eprint/36743

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