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Severe digital necrosis in an elderly patient with heterozygous factor V Leiden mutation

Patel, G. K., Morris, E., Rashid, M. R. and Anstey, Alexander Vincent 2000. Severe digital necrosis in an elderly patient with heterozygous factor V Leiden mutation. British Journal of Dermatology 143 (6) , pp. 1302-1305. 10.1046/j.1365-2133.2000.03906.x

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Abstract

We report an 81-year-old female with a heterozygous factor V Leiden mutation who developed purpura fulminans. Digital necrosis, a characteristic clinical feature of purpura fulminans was prominent. Purpura fulminans is more common in children and adult cases are rare. Of eight reported cases of purpura fulminans resulting from a heterozygous factor V Leiden mutation recorded in the literature, only two were in adults: 40 and 42 years of age, respectively. This is the first report of this condition arising in a patient in her eighties.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > RL Dermatology
Uncontrolled Keywords: digital necrosis, factor V Leiden, protein C, purpura fulminans
Publisher: Blackwell Publishing
ISSN: 0007-0963
Last Modified: 19 Mar 2016 23:02
URI: http://orca-mwe.cf.ac.uk/id/eprint/36159

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