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Role of interleukin 18 in rheumatoid arthritis

Liew, Foo Y., Wei, Xiao-Qing and McInnes, I. B. 2003. Role of interleukin 18 in rheumatoid arthritis. Annals Of The Rheumatic Diseases 62 , pp. 48-50. 10.1136/ard.62.suppl_2.ii48

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Abstract

Mediators produced by innate immune response cells such as macrophages can profoundly influence adaptive immunity. Recent studies have shown that interleukin (IL) 18 has an influential role in inflammatory response. Recent data are presented illustrating the importance of IL18 in the induction and perpetuation of chronic inflammation during experimental and clinical rheumatoid synovitis. These findings suggest that antagonists to IL18 may have a role in the treatment of organ specific autoimmune diseases.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Dentistry
Subjects: R Medicine > R Medicine (General)
Publisher: BMJ Publishing Group
Last Modified: 04 Jun 2017 04:16
URI: http://orca-mwe.cf.ac.uk/id/eprint/35694

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