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Diamond based ion-sensitive field effect transistors for cellular biosensing

Bennett, A., Gaudin, O., Williams, Oliver Aneurin, Foord, J. S. and Jackman, R. B. 2007. Diamond based ion-sensitive field effect transistors for cellular biosensing. Presented at: 2006 MRS Fall Meeting, Boston, MA, USA, 27 November - 1 December 2006. Symposium J – Diamond Electronics—Fundamentals to Applications. MRS Proceedings , vol. 956. Cambridge: Cambridge University Press, pp. 221-227. 10.1557/PROC-0956-J16-03

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The use of a chemically inert and essentially biocompatible material for cellular biosensing is an attractive idea. In this context we have studied the operation of diamond-based ion-sensitive field effect transistors (ISFETs) within solutions of varying pH, and alkali-halide concentrations. In particular, we report the use of an inexpensive diamond substrate material, often referred to as ‘black’ diamond. pH sensitivity was observed when devices based on hydrogen-terminated p-type surfaces where employed, provide some surface oxidation was performed prior to their use. Variation in the threshold voltage for ISFET operation of the order of 20mV/pH unit was determined. In terms of operation in potassium iodide solution, we have shown that the device is shows selective sensitivity to the iodide species, despite the equi-molar presence of both K+ and I- species. The origin of this selectivity is discussed.

Item Type: Conference or Workshop Item (Paper)
Date Type: Publication
Status: Published
Schools: Physics and Astronomy
Subjects: Q Science > QC Physics
Uncontrolled Keywords: diamond; devices; sensor
Publisher: Cambridge University Press
Last Modified: 04 Jun 2017 04:11

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