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Abnormal spatial and non-spatial cueing effects in mild cognitive impairment and Alzheimer's disease

Tales, Andrea, Snowden, Robert Jefferson, Haworth, Judy Margaret and Wilcock, Gordon 2005. Abnormal spatial and non-spatial cueing effects in mild cognitive impairment and Alzheimer's disease. Neurocase 11 (1) , pp. 85-92. 10.1080/13554790490896983

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Abstract

Our aim was to further characterize the clinical concept of mild cognitive impairment (MCI). We examined visual attention-related processing in 12 patients with amnestic MCI, 16 healthy older adults and 16 patients with Alzheimer’s disease (AD) by measuring performance on computer-based tests of attentional disengagement, alerting ability, and inhibition of return. Unlike the healthy older controls, the patients with AD and the patients with amnestic MCI exhibited a significant detriment in both the ability to disengage attention from an incorrectly cued location and the ability to use a visual cue to produce an alerting effect. The pattern of results displayed by the MCI group indicates that patients who only appear clinically to suffer from a deficit in memory also display a deficit in specific aspects of visual attention-related processing, which closely resemble the magnitude seen in AD.

Item Type: Article
Status: Published
Schools: Psychology
Subjects: R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Publisher: Taylor & Francis
ISSN: 1355-4794
Last Modified: 04 Jun 2017 04:06
URI: http://orca-mwe.cf.ac.uk/id/eprint/32646

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