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Modelling the response of whispering-gallery-mode optical resonators for biosensing applications

Langbein, Wolfgang Werner, Chantada, Laura, Nikolaev, Nikolay Irmanov, Ivanov, Alexei and Borri, Paola 2009. Modelling the response of whispering-gallery-mode optical resonators for biosensing applications. Presented at: Nanoscale imaging, sensing, and actuation for biomedical applications 6, San Jose, CA, USA, 27-28 January 2009. Published in: Cartwright, A. N. and Nicolau, D. V. eds. Proceedings of the Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI conference, San Jose, USA, 27 January 2009. Proceedings of SPIE , vol. 7188. Bellingham, WA: SPIE, 71880G. 10.1117/12.808790

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Abstract

We present a theoretical analysis of the response of whispering gallery modes for biosensing applications, studied numerically in microcylinders and semi-analytically in microspheres. The effect of single and multiple particles is calculated, simulating biological analytes of different sizes and polarizabilities attached to the microresonator surface. Besides whispering-gallery-mode frequency shifts, we find that also broadenings and splittings (from lifted rotational symmetry) appear due to particles attachment and/or the vicinity to a planar coupler. For a single analyte, both particle size and refractive index can be determined from the broadening and shift, opening the perspective to a new biosensing modality.

Item Type: Conference or Workshop Item (Paper)
Date Type: Publication
Status: Published
Schools: Physics and Astronomy
Biosciences
Subjects: Q Science > QC Physics
Q Science > QH Natural history > QH301 Biology
Uncontrolled Keywords: Biosensing ; Microresonators ; Modeling ; Optical resonators ; Particles ; Polarizability ; Refractive index
Publisher: SPIE
ISBN: 9780819474346
Last Modified: 07 Jun 2019 20:45
URI: http://orca-mwe.cf.ac.uk/id/eprint/27363

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