Farid, Umar and Wirth, Thomas 2012. Highly stereoselective metal-free oxyaminations using chiral hypervalent iodine reagents. Angewandte Chemie. International Edition 51 (14) , pp. 3462-3465. 10.1002/anie.201107703 |
Official URL: http://dx.doi.org/10.1002/anie.201107703
Abstract
The ring and I: Hypervalent iodine compounds avoid the issues of toxicity or complicated ligands of many transition-metal-based systems. A highly enantioselective oxyamination of alkenes with N-sulfonyl ureas employing chiral, lactic acid-based hypervalent iodine reagents gives a facile synthesis of enantiomerically pure 2-arylproline derivatives (see scheme) for the first time.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Chemistry |
Subjects: | Q Science > QD Chemistry |
Uncontrolled Keywords: | Amino alcohols; Aminohydroxylation; Cyclization; Hypervalent iodine; Stereoselective synthesis |
Publisher: | Wiley-Blackwell |
ISSN: | 1433-7851 |
Last Modified: | 04 Jun 2017 03:48 |
URI: | http://orca-mwe.cf.ac.uk/id/eprint/26908 |
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