Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Human papillomavirus infection in Barrett's oesophagus in the UK: an infrequent event

Rai, N., Jenkins, G. J. S., McAdam, E., Hibbitts, Samantha Jayne, Fiander, Alison Nina and Powell, Ned George 2008. Human papillomavirus infection in Barrett's oesophagus in the UK: an infrequent event. Journal of Clinical Virology 43 (2) , pp. 250-252. 10.1016/j.jcv.2008.07.004

Full text not available from this repository.

Abstract

Background Human papillomavirus (HPV) infection has been reported in squamous cell carcinomas of the oesophagus and has been recently described in Barrett's oesophagus, a premalignant condition which may give rise to oesophageal adenocarcinoma. Objectives To investigate HPV infection in Barrett's oesophagus in a UK population. Study design DNA was extracted from 73 Barrett's oesophagus biopsies and examined for the presence of DNA for 14 high risk (HR) and 6 low risk (LR) HPV types. Results HPV DNA was present in only 1 of 73 samples; genotyping indicated this was a high risk type 51 infection. Conclusions HPV infection appears unlikely to be a significant factor in the aetiology of Barrett's oesophagus in the UK.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > RG Gynecology and obstetrics
Uncontrolled Keywords: HPV, Barrett's oesophagus, adenocarcinoma, squamous cell carcinoma
Publisher: Elsevier
ISSN: 1386-6532
Last Modified: 06 Feb 2020 22:45
URI: https://orca.cardiff.ac.uk/id/eprint/25996

Citation Data

Cited 26 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item