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Stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans using an intramolecular allylation strategy employing allylsilanes

Jervis, Peter J., Kariuki, Benson and Cox, Liam R. 2008. Stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans using an intramolecular allylation strategy employing allylsilanes. Tetrahedron Letters 49 (16) , pp. 2514-2518. 10.1016/j.tetlet.2008.02.088

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Abstract

A Bronsted acid-mediated intramolecular allylation involving an allylsilane and an aldehyde has been used as the key step in a stereoselective synthesis of 3,4-disubstituted tetrahydrofurans and 2,3,4-trisubstituted tetrahydrofurans.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: Pergamon-Elsevier Science
ISSN: 0040-4039
Last Modified: 04 Jun 2017 03:43
URI: http://orca-mwe.cf.ac.uk/id/eprint/25354

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