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Yersinia pseudotuberculosis is resistant to killing by human neutrophils

Laws, T. R., Davey, Martin S., Green, Christopher, Cooper, Ian A. M., Titball, Richard W. and Lukaszewski, Roman A. 2011. Yersinia pseudotuberculosis is resistant to killing by human neutrophils. Microbes And Infection 13 (6) , pp. 607-611.

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The interaction between humanneutrophils and the Gram negative gastrointestinal pathogen Yersiniapseudotuberculosis was investigated in vitro. Despite the wealth of data describing how Yersinia can affect the function of neutrophils, there are no published studies describing if neutrophil cells can affect the viability of Y. pseudotuberculosis. The wild-type IP32953 strain of Y. pseudotuberculosis was found to be resistant to killing by humanneutrophils. Confocal examination and flow-cytometric analysis of this interaction revealed that bacteria were taken up.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Publisher: Elsevier Masson SAS
ISSN: 1286-4579
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Last Modified: 19 Mar 2016 22:39

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