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Very good inter-rater reliability of Engel and ILAE epilepsy surgery outcome classifications in a series of 76 patients

Durnford, Andrew, Rodgers, William, Kirkham, Fenella, Mullee, Mark, Whitney, Andrea, Prevett, Martin, Kinton, Lucy, Harris, Matthew and Gray, William Peter 2011. Very good inter-rater reliability of Engel and ILAE epilepsy surgery outcome classifications in a series of 76 patients. Seizure - European Journal of Epilepsy 20 (10) , pp. 809-812. 10.1016/j.seizure.2011.08.004

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Abstract

The inter-rater reliability, expressed as kappa score, k, of the Engel and International League Against Epilepsy (ILAE) classifications of epilepsy surgery seizure outcome has not previously been evaluated. In a consecutive series of 76 patients (40 male; 25 children), 75 undergoing resective and 1 disconnective surgery at a mean age of 27.5 years (13 months–62 years), one observer classified 88% (n = 67) and a second observer classified 87% (n = 66) of patients as either Engel I or II (free from or rare disabling seizures) after a median follow up of 36 months (range 12–92 months); comparably, both observers classified 84% (n = 64) as ILAE 1–3. Correlation for Engel versus ILAE for observer 1 was 0.933 (p < .0005) and for observer 2 was 0.931 (p < .0005). Both ILAE (k 0.81, 95% confidence intervals 0.69, 0.91) and Engel (k 0.77, 95% CI 0.65, 0.87) classifications have very acceptable inter-rater reliability as well as significant correlation.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG)
Medicine
Subjects: Q Science > Q Science (General)
R Medicine > R Medicine (General)
Uncontrolled Keywords: inter-rater; outcome; epilepsy surgery; ILAE; Engel
Publisher: Elsevier
ISSN: 1059-1311
Last Modified: 04 Jun 2017 03:20
URI: http://orca-mwe.cf.ac.uk/id/eprint/19927

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