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Synthesis of substituted quinazolin-4(3h)-ones and quinazolines via directed lithiation

El-Hiti, Gamal A. 2000. Synthesis of substituted quinazolin-4(3h)-ones and quinazolines via directed lithiation. Heterocyles 53 (8) , pp. 1839-1868. 10.3987/REV-00-535

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Abstract

Various quinazolin-4(3H)-ones and quinazolines were successfully lithiated using different lithiating reagents at low temperature. Reactions of the lithio reagents thus obtained with a variety of electrophiles afforded the corresponding substituted derivatives in very good yields.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Uncontrolled Keywords: Alkyllithium ; Diazine ; Dilithio Reagent ; Electrophile Metalation
Publisher: Japan Institute of Heterocyclic Chemistry
ISSN: 1881-0942
Last Modified: 19 Mar 2016 22:24
URI: http://orca-mwe.cf.ac.uk/id/eprint/15366

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