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Corrigendum: Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells

Tan, Jennifer Y., Sirey, Tamara, Honti, Frantisek, Graham, Bryony, Piovesan, Allison, Merkenschlager, Matthias, Webber, Caleb, Ponting, Chris P. and Marques, Ana C. 2015. Corrigendum: Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells. Genome Research 25 (9) , 1410.1. 10.1101/gr.196568.115

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Abstract

In the above-mentioned article, one result reported in the third paragraph of the Results subsection “ceRNAts of individual lnceRNAs tend to be functionally related” was in error. This paragraph should now read: “On average, mESC-expressed lnceRNAs have 20.2 predicted MREs per kb of transcript that are specific to 12 different mESC-expressed miRNAs. This MRE density is similar to the density within 3′ UTRs of ceRNAts (20.4 MREs predicted per kb; P = 0.34, two-tailed Mann-Whitney U test) (Supplemental Fig. S9; Supplemental Table S8). A single lnceRNA might, therefore, be as likely as an mRNA to regulate post-transcriptionally the transcript abundance of many mRNAs via crosstalk with many miRNAs.” Corrected versions of Supplemental Figure S9 and Supplemental Table S8 are also now provided online. This correction does not affect any of the conclusions of the paper. The authors apologize for any confusion caused by this error.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Additional Information: Original article archived at http://orca.cf.ac.uk/135801
Publisher: Cold Spring Harbor Laboratory Press
ISSN: 1088-9051
Date of First Compliant Deposit: 22 October 2020
Last Modified: 22 Oct 2020 13:45
URI: http://orca-mwe.cf.ac.uk/id/eprint/135800

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