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Antibiotic exposure and the risk of colorectal adenoma and carcinoma: systematic review and meta-analysis of observational studies

Sanyaolu, Leigh N., Oakley, Natalie J., Nurmatov, Ulugbek, Dolwani, Sunil and Ahmed, Haroon 2019. Antibiotic exposure and the risk of colorectal adenoma and carcinoma: systematic review and meta-analysis of observational studies. Colorectal Disease 10.1111/codi.14921
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Abstract

The Incidence of colorectal cancer (CRC) is increasing, and evidence suggests that maladaptation of the bowel microbiome may be associated with colorectal carcinogenesis. Consumption of antibiotics may cause imbalance of the bowel microbiome but research assessing an association between antibiotic exposure and CRC is inconsistent. The aim of this systematic review and meta‐analysis was to appraise and synthesize the available evidence.

Item Type: Article
Date Type: Published Online
Status: In Press
Schools: Medicine
Publisher: Wiley
ISSN: 1462-8910
Date of First Compliant Deposit: 25 November 2019
Date of Acceptance: 17 November 2019
Last Modified: 17 Jan 2020 16:31
URI: http://orca-mwe.cf.ac.uk/id/eprint/127105

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