Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Unexpected products from carbonylation of lithiated quinazolin-4(3H)-one derivatives

Smith, Keith, El-Hiti, Gamal and Abdel-Megeed, M. F. 2003. Unexpected products from carbonylation of lithiated quinazolin-4(3H)-one derivatives. Russian Journal of Organic Chemistry = Zhurnal Organicheskoi Khimii 39 (3) , pp. 430-435. 10.1023/A:1025558201900

Full text not available from this repository.

Abstract

Doubly lithiated 3-pivaloylaminoquinazolin-4(3H)-one reacts with carbon(II) oxide at 0°C to give 77% of a mixture of azetidinone and indole derivatives, each incorporating a diisopropylamide unit from lithium diisopropylamide used for lithiation. No analogous reaction occurs with doubly lithiated 3-acetylaminoquinazolin-4(3H)-one and 3-acyl-2-alkylquinazolin-4(3H)-one. Carbonylation of doubly lithiated 2-alkyl-3-aminoquinazolin-4(3H)-ones at 0°C results in deamination to give 2-alkylquinazolin-4(3H)-ones in good yields.

Item Type: Article
Status: Published
Schools: Chemistry
Subjects: Q Science > QD Chemistry
Publisher: Springer Verlag
ISSN: 1070-4280
Last Modified: 04 Jun 2017 02:51
URI: http://orca-mwe.cf.ac.uk/id/eprint/12704

Citation Data

Cited 14 times in Google Scholar. View in Google Scholar

Cited 16 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item