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The protide prodrug technology: Where next?

Alanazi, Ashwag S., James, Edward and Mehellou, Youcef 2019. The protide prodrug technology: Where next? ACS Medicinal Chemistry Letters 10 (1) , pp. 2-5. 10.1021/acsmedchemlett.8b00586

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Abstract

The ProTide prodrug technology has proved very useful in the discovery of nucleotide therapeutics and has successfully led to two FDA-approved drugs. However, with the extensive application of this prodrug approach to nucleotides for nearly three decades, the intellectual property (IP) landscape is becoming congested and, to overcome this, new inventive applications of the ProTide prodrug technology are emerging.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Pharmacy
Publisher: American Chemical Society
ISSN: 1948-5875
Date of First Compliant Deposit: 2 January 2019
Date of Acceptance: 15 December 2018
Last Modified: 15 Mar 2020 03:26
URI: http://orca-mwe.cf.ac.uk/id/eprint/117958

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