Obesity and fertility

Best, Damian and Bhattacharya, Siladitya ORCID: https://orcid.org/0000-0002-4588-356X 2015. Obesity and fertility. Hormone Molecular Biology and Clinical Investigation 24 (1) , pp. 5-10. 10.1515/hmbci-2015-0023

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Abstract

The prevalence of overweight and obesity in women of reproductive age has increased over the past 30 years. Infertility affects 1 in 7 couples, and female obesity is associated with anovulation. The mechanisms by which excessive fat delays time to pregnancy (TTP) appear rooted in ovulatory problems and direct effects on oocytes, causing poorer embryo development, as well as in effects on the endometrium. Weight loss in women has been shown to improve conception, but not necessarily live birth rates following fertility treatment, and further research in this area is needed. The obesity epidemic has been accompanied by a potential rise in male infertility, which has been attributed to hormonal disturbances and compromised semen parameters.

Item Type:	Article
Date Type:	Publication
Status:	Published
Schools:	Medicine
Publisher:	De Gruyter
ISSN:	1868-1891
Date of Acceptance:	13 July 2013
Last Modified:	24 Oct 2022 08:20
URI:	https://orca.cardiff.ac.uk/id/eprint/117442

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