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Focal therapy in primary localised prostate cancer: The European Association of Urology position in 2018

van der Poel, Henk G., van den Bergh, Roderick C.N., Briers, Erik, Cornford, Philip, Govorov, Alex, Henry, Ann M., Lam, Thomas B., Mason, Malcolm David, Rouvière, Olivier, De Santis, Maria, Willemse, Peter-Paul M., van Poppel, Hendrik and Mottet, Nicolas 2018. Focal therapy in primary localised prostate cancer: The European Association of Urology position in 2018. European Urology 74 (1) , pp. 84-91. 10.1016/j.eururo.2018.01.001

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Abstract

Radical treatment of localised prostate cancer is recognised to be an unnecessary intervention or overtreatment in many men. Consequently, there has been a rapid uptake in the use of focal ablative therapies. However, there are several biological and practical concerns about such approaches as they have yet to be proved as robust treatment options. In particular, the multifocal nature of prostate cancer argues against unifocal treatment, while limitations in imaging can preclude the accurate identification of the number, location, and extent of prostate cancer foci. To date, a number of ablative options have reported results on mainly low-risk disease. Most series are relatively immature, with a lack of consistent follow-up, and the morbidity of retreatment is often not considered. The authors consider focal therapy to be an investigational modality, and encourage prospective recording of outcomes and recruitment of suitable patients.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Elsevier
ISSN: 0302-2838
Date of First Compliant Deposit: 20 July 2018
Date of Acceptance: 2 January 2018
Last Modified: 27 Jun 2019 12:31
URI: http://orca-mwe.cf.ac.uk/id/eprint/113341

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