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Movement disorders and syndromic autism: a systematic review

Bell, L., Wittkowski, A. and Hare, D. J. 2019. Movement disorders and syndromic autism: a systematic review. Journal of Autism and Developmental Disorders 49 (1) , pp. 54-67. 10.1007/s10803-018-3658-y

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Abstract

Movement disorders are reported in idiopathic autism but the extent to which comparable movement disorders are found in syndromic/co-morbid autism is unknown. A systematic search of Medline, Embase, PsychINFO and CINAHL on the prevalence of specific movement disorder in syndromic autism associated with specific genetic syndromes identified 16 papers, all relating to Angelman syndrome or Rett syndrome. Prevalence rates of 72.7–100% and 25.0–27.3% were reported for ataxia and tremor, respectively, in Angelman syndrome. In Rett syndrome, prevalence rates of 43.6–50% were reported for ataxia and 27.3–48.3% for tremor with additional reports of dystonia, rigidity and pyramidal signs. However, reliable assessment measures were rarely used and recruitment was often not described in sufficient detail.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Psychology
Publisher: Springer Verlag
ISSN: 0162-3257
Date of First Compliant Deposit: 18 July 2018
Date of Acceptance: 15 June 2018
Last Modified: 28 Jul 2020 01:24
URI: http://orca-mwe.cf.ac.uk/id/eprint/113247

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