Cardiff University | Prifysgol Caerdydd ORCA
Online Research @ Cardiff 
WelshClear Cookie - decide language by browser settings

Atrial natriuretic peptide inhibits the release of endothelium-derived relaxing factor from blood vessels of the rabbit

Hogan, J. C., Warden-Smith, Jeremy, Richards, A. C. and Lewis, Malcolm John 1989. Atrial natriuretic peptide inhibits the release of endothelium-derived relaxing factor from blood vessels of the rabbit. European Journal of Pharmacology 165 (1) , pp. 129-134. 10.1016/0014-2999(89)90778-4

Full text not available from this repository.

Abstract

We investigated the effects of atrial natriuretic peptide (ANP) on release of endothelium-derived relaxing factor (EDRF) from rabbit aorta and central ear artery using inhibition of platelet aggregation and vascular smooth muscle relaxation respectively as measures of EDRF activity. ANP at concentrations greater than 10(-9) M inhibited carbachol-induced EDRF release from rabbit aorta and acetylcholine-induced EDRF release from the central ear artery. These findings are consistent with previous observations that 8-bromo cyclic GMP inhibits EDRF release from rabbit aorta and ANP inhibits release of EDRF from cultured endothelial cells.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Medicine
Pharmacy
Subjects: R Medicine > R Medicine (General)
R Medicine > RS Pharmacy and materia medica
Uncontrolled Keywords: Endothelium-derived relaxing factor (EDRF); Atrial natriuretic peptide (ANP); Aorta; Central ear artery; (Rabbit)
Publisher: Elsevier
ISSN: 0014-2999
Last Modified: 04 Jun 2017 02:12
URI: http://orca-mwe.cf.ac.uk/id/eprint/10869

Citation Data

Cited 12 times in Google Scholar. View in Google Scholar

Cited 10 times in Scopus. View in Scopus. Powered By Scopus® Data

Actions (repository staff only)

Edit Item Edit Item