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The influence of endocardial endothelium on myocardial contraction

Warden-Smith, Jeremy, Shah, Ajay M., Fort, S and Lewis, Malcolm John 1992. The influence of endocardial endothelium on myocardial contraction. Trends in Pharmacological Sciences 13 (3) , pp. 113-116. 10.1016/0165-6147(92)90040-D

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A novel unidentified agent, provisionally named 'endocardin', has been shown to be released from endocardial endothelium. Endocardin has a unique prolonging effect on myocardial contraction. In contrast, endothelium-derived relaxing factor released from endocardial endothelium has the opposite effect of abbreviating contraction. Jerry Smith and colleagues discuss the mechanisms of action of these agents and their possible physiology and pathophysiology.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
Publisher: Elsevier
ISSN: 0165-6147
Last Modified: 04 Jun 2017 02:12

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