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Can emotional and behavioral dysregulation in youth be decoded from functional neuroimaging?

Antal, Andrea, Portugal, Liana C. L., Rosa, Maria João, Rao, Anil, Bebko, Genna, Bertocci, Michele A., Hinze, Amanda K., Bonar, Lisa, Almeida, Jorge R. C., Perlman, Susan B., Versace, Amelia, Schirda, Claudiu, Travis, Michael, Gill, Mary Kay, Demeter, Christine, Diwadkar, Vaibhav A., Ciuffetelli, Gary, Rodriguez, Eric, Forbes, Erika E., Sunshine, Jeffrey L., Holland, Scott K., Kowatch, Robert A., Birmaher, Boris, Axelson, David, Horwitz, Sarah M., Arnold, Eugene L., Fristad, Mary A., Youngstrom, Eric A., Findling, Robert L., Pereira, Mirtes, Oliveira, Leticia, Phillips, Mary Louise and Mourao-Miranda, Janaina 2016. Can emotional and behavioral dysregulation in youth be decoded from functional neuroimaging? PLoS ONE 11 (1) , e0117603. 10.1371/journal.pone.0117603

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High comorbidity among pediatric disorders characterized by behavioral and emotional dysregulation poses problems for diagnosis and treatment, and suggests that these disorders may be better conceptualized as dimensions of abnormal behaviors. Furthermore, identifying neuroimaging biomarkers related to dimensional measures of behavior may provide targets to guide individualized treatment. We aimed to use functional neuroimaging and pattern regression techniques to determine whether patterns of brain activity could accurately decode individual-level severity on a dimensional scale measuring behavioural and emotional dysregulation at two different time points.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Medicine
Publisher: Public Library of Science
ISSN: 1932-6203
Date of First Compliant Deposit: 25 July 2017
Date of Acceptance: 15 December 2015
Last Modified: 19 Jun 2019 10:35

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