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In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p

Kent, Nicholas A., Karabetsou, Nickoletta, Politis, Panagiotis K. and Mellor, Jane 2001. In vivo chromatin remodeling by yeast ISWI homologs Isw1p and Isw2p. Genes and Development 15 , pp. 619-626. 10.1101/gad.190301

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Abstract

Isw1p and Isw2p are budding yeast homologs of the DrosophilaISWI chromatin-remodeling ATPase. Using indirect-end-label and chromatin immunoprecipitation analysis, we show both independent and cooperative Isw1p- and Isw2p-mediated positioning of short nucleosome arrays in gene-regulatory elements at a variety of transcription units in vivo. We present evidence that both yeast ISWI complexes regulate developmental responses to starvation and that for Isw2p, recruitment by different DNA-binding proteins controls meiosis and haploid invasive growth.

Item Type: Article
Date Type: Publication
Status: Published
Schools: Biosciences
ISSN: 0890-9369
Date of First Compliant Deposit: 30 March 2016
Last Modified: 04 Jun 2017 01:37
URI: http://orca-mwe.cf.ac.uk/id/eprint/1020

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