Morrison, Peter W. J. ORCID: https://orcid.org/0000-0002-3712-7908 and Khutoryanskiy, Vitaliy V 2014. Advances in ophthalmic drug delivery. Therapeutic Delivery 5 (12) , pp. 1297-1315. 10.4155/tde.14.75 |
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Abstract
Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The use of drug-loaded contact lenses and ocular inserts allows drugs to be better placed where they are needed for more direct delivery. Developments in ocular implants gives a means to overcome the physical barriers that traditionally prevented effective treatment. Implant technologies are under development allowing long-term drug delivery from a single procedure, these devices allow posterior chamber diseases to be effectively treated. Future developments could bring artificial corneas to eliminate the need for donor tissue and one-off implantable drug depots lasting the patient's lifetime.
Item Type: | Article |
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Date Type: | Publication |
Status: | Published |
Schools: | Pharmacy |
Subjects: | R Medicine > RE Ophthalmology R Medicine > RM Therapeutics. Pharmacology |
Publisher: | Future Science |
ISSN: | 2041-5990 |
Date of First Compliant Deposit: | 30 May 2017 |
Date of Acceptance: | 8 December 2014 |
Last Modified: | 12 Nov 2023 17:17 |
URI: | https://orca.cardiff.ac.uk/id/eprint/100972 |
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